Foundations of Clinical Research

Foundations of Clinical Research

Applications to Evidence-Based Practice

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Contents:

PART 1 Foundations of Research and Evidence

Frameworks for Generating and Applying Evidence

On the Road to Translational Research

Defining the Research Question

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PART 2 Concepts of Measurement

Principles of Measurement

Concepts of Measurement Reliability

Concepts of Measurement Validity

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PART 3 Designing Clinical Research

Choosing a Sample

Principles of Clinical Trials

Design Validity

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PART 4 Analyzing Data

Descriptive Statistics

Foundations of Statistical Inference

Comparing Two Means:The t-Test

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PART 5 Putting It All Together

Writing a Research Proposal

Critical Appraisal: Evaluating Research Reports

Synthesizing Literature: Systematic Reviews and Meta-Analyses

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Appendices

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About Book:
As new scientific information becomes available through basic and clinical research, recommended treatments and drug therapies undergo changes. The author(s) and publisher have done everything possible to make this book accurate, up to date, and in accord with accepted standards at the time of publication. The author(s), editors, and publisher are not responsible for errors or omissions or for consequences from application of the book and make no warranty, expressed or implied, in regard to the contents of the book. Any practice described in this book should be applied by the reader in accordance with professional standards of care used in regard to the unique circumstances that may apply in each situ-ation. The reader is advised always to check product information (package inserts) for changes and new information regarding dosage and contraindications before administering any drug. Caution is especially urged when using new or infrequently ordered drugs.